3. Buick LaCrosse eAssist - 648
Buick’s large and lovely LaCrosse earns a bronze medal in today’s mileage melee. The eAssist version is the thriftiest model and it really goes the distance, capable of devouring nearly 650 miles of open road on a single tank.
SEE ALSO: 2013 Buick LaCrosse Review
It holds 18 gallons of gasoline and is rated by the EPA at 25 MPG city and 36 highway. Under the hood this mild hybrid is powered by a 2.4-liter four-cylinder engine. An electric motor and a small lithium-ion battery provide up to 15 additional horsepower.