3. Mercedes-Benz C-Class - 66,596 units
Naturally, the Mercedes-Benz entry-level sedan is also towards the top of the list of best selling luxury vehicles in America. The C250 model starts at $36,725 with a 1.8-liter, turbocharged four-cylinder lurking under the hood. The powerplant features 201 hp and is mated to a seven-speed automatic transmission, helping the sedan net 22 mpg in the city and 31 mpg on the highway.